Clients are increasingly drawn towards aesthetic treatments that use natural substances and that culminate in natural results. Polynucleotides offer both of these benefits, utilising the DNA found in salmon and trout sperm, which kickstarts the body’s own production of new cells.
By stimulating the body’s own process of cell production and renewal, skin looks better and more revitalised, without the need for synthetic substances and injectables.
But how do polynucleotides represent the future of regenerative aesthetics, and what are the immediate and long-term benefits of these injections for clients?
How Does Polynucleotide Treatment Boost Skin Rejuvenation?
Polynucleotide treatment is a regenerative aesthetic treatment, not a substance in itself. Polynucleotides are long chains of nucleotides the natural building blocks of DNA and RNA which, in aesthetics, are used as injectable biostimulators to improve overall skin quality.
Derived from purified salmon or trout DNA, polynucleotides work by stimulating fibroblasts within the skin. Once injected, they encourage tissue repair, boost collagen and elastin production, and significantly improve hydration and elasticity. Over time, this helps to soften fine lines, calm inflammation, and restore a healthier, more youthful appearance.
Rather than adding artificial volume like fillers or freezing muscles like Botox, polynucleotide treatment supports the skin’s own regenerative processes. It addresses the root causes of skin ageing such as collagen loss, dehydration, and reduced elasticity allowing the skin to repair and revitalise itself naturally.
The Benefits of Polynucleotide Treatment
Polynucleotide treatment is offered through injections which are targeted in their position, and which can be used anywhere including the face, eyes, neck, scalp, chest, hands, arms, stomach, and knees, as well as localised scars and imperfections.
Far from adding artificial volume, these injections enhance the skin’s natural regenerative abilities, which crucially means that the results are always incredibly natural for clients. They don’t alter the facial structure or appearance; rather, they enhance the natural assets and features.
Other benefits of polynucleotide treatment, aside from its regenerative and wholly natural results, include the minimal side effects thanks to the shallow injections and the versatility of treatment, which means clients can adjust the treatment schedule according to their goals and aesthetician recommendations.
The versatility of these injections also means they pose other benefits, including scalp stimulation and hair regrowth.
Who is Polynucleotide Treatment For – and is it Right for You?
Polynucleotide treatments are designed to help reverse signs of ageing by injecting a stimulant to help the body produce more collagen, elastin, and healthy cells. Treatment duration and scheduling vary from one client to the next, with our advice typically being to reach out to our team of aestheticians to discuss your ideal results and goals.
Polynucleotide treatment doesn’t change the composition of the skin or alter the layers beneath it. Instead, it enhances what’s already there and ignites the body to activate its own regenerative processes, one cell at a time. The benefits of this vary, but clients are always happy with the results.
Get in touch to find out more about how this treatment option could benefit you.


